[HTML][HTML] The class A scavenger receptor binds to proteoglycans and mediates adhesion of macrophages to the extracellular matrix
J Santiago-Garcı́a, T Kodama, RE Pitas - Journal of Biological Chemistry, 2003 - ASBMB
The class A scavenger receptor (SR-A) binds modified lipoproteins and has been implicated
in cholesterol ester deposition in macrophages. The SR-A also contributes to cellular
adhesion. Using SR-A+/+ andSR-A−/− murine macrophages, we found SR-A expression
important for both divalent cation-dependent and-independent adhesion of macrophages to
the human smooth muscle cell extracellular matrix. The SR-A mediated 65 and 85% of
macrophage adhesion to the extracellular matrix in the presence and absence of serum …
in cholesterol ester deposition in macrophages. The SR-A also contributes to cellular
adhesion. Using SR-A+/+ andSR-A−/− murine macrophages, we found SR-A expression
important for both divalent cation-dependent and-independent adhesion of macrophages to
the human smooth muscle cell extracellular matrix. The SR-A mediated 65 and 85% of
macrophage adhesion to the extracellular matrix in the presence and absence of serum …