The inhibition of telomerase activity in actively dividing cells leads to suppression of cell
growth after a time delay (inhibitory delay) required to reach a threshold telomeric DNA size.
We developed a mathematical model of the dynamics of telomere size distribution and cell
growth in the presence of telomere inhibitors that allowed quantification of the inhibitory
delay. The model based on the solution of a system of differential equations described
quantitatively recent experimental data on dynamics of cultured cells in presence of …