Effectiveness of sotalol treatment in symptomatic Brugada syndrome

KA Glatter, Q Wang, M Keating, S Chen… - The American journal of …, 2004 - Elsevier
KA Glatter, Q Wang, M Keating, S Chen, N Chiamvimonvat, MM Scheinman
The American journal of cardiology, 2004Elsevier
We describe a 53-year-old man with recurrent syncopal events and a malignant family
history who was treated for 13 years with sotalol drug therapy with no further occurrence of
Brugada syndrome symptoms. Genetic testing revealed that he carried a Brugada syndrome
sodium channel SCN5A mutation (4189delT). This finding suggests that sotalol may be of
therapeutic benefit in such patients.
We describe a 53-year-old man with recurrent syncopal events and a malignant family history who was treated for 13 years with sotalol drug therapy with no further occurrence of Brugada syndrome symptoms. Genetic testing revealed that he carried a Brugada syndrome sodium channel SCN5A mutation (4189delT). This finding suggests that sotalol may be of therapeutic benefit in such patients.
Elsevier