The progression of invasiveness regarding the role of transforming growth factor β receptor type II in gastric cancer
M Tateishi, I Kusaba, H Masuda, T Tanaka… - European Journal of …, 2000 - Elsevier
Aims Transforming growth factor β (TGFβ) is a potent growth inhibitor of epithelial cells. The
expression of TGFβ receptors is required for the effect of TGFβ. In this study, we used
immunohistochemistry to demonstrate the roles of the expression of TGFβ type I (TβR-I) and
type II (TβR-II) receptors in the progression of gastric carcinoma. Methods To evaluate the
potential prognostic value of TβR-I and TβR-II, 158 consecutive gastric cancer tissues
specimens obtained over a 3-year period were examined. Results A total of 50 (32%) and …
expression of TGFβ receptors is required for the effect of TGFβ. In this study, we used
immunohistochemistry to demonstrate the roles of the expression of TGFβ type I (TβR-I) and
type II (TβR-II) receptors in the progression of gastric carcinoma. Methods To evaluate the
potential prognostic value of TβR-I and TβR-II, 158 consecutive gastric cancer tissues
specimens obtained over a 3-year period were examined. Results A total of 50 (32%) and …