[HTML][HTML] Mononuclear leukocytes preferentially bind via CD44 to hyaluronan on human intestinal mucosal smooth muscle cells after virus infection or treatment with …

CA de la Motte, VC Hascall, A Calabro… - Journal of Biological …, 1999 - ASBMB
Pathological changes in inflammatory bowel disease include an increase in intestinal
mucosal mononuclear leukocytes and hyperplasia of the muscularis mucosae smooth
muscle cells (M-SMCs). Because virus infections have correlated with disease flare, we
tested the response of cultured M-SMCs to respiratory syncytial virus, measles virus, and the
viral analogue, poly (I· C). Adhesion of U937 cells and peripheral blood mononuclear cells
was used to measure the leukocyte-interactive potential of M-SMCs. Untreated M-SMCs …