Risk of dementia in first-degree relatives of patients with Alzheimer's disease and related disorders

R Mayeux, M Sano, J Chen, T Tatemichi… - Archives of …, 1991 - jamanetwork.com
• First-degree relatives of patients with Alzheimer's disease (AD) are at greater risk for
dementia when compared with the relatives of their healthy peers, but not when compared
with the relatives of patients with Parkinson's disease. This may indicate that the risk of
dementia in these relatives is not specific to AD or that these studies are biased. We
obtained a family history and vital status information on each first-degree relative of patients
attending a clinic and in a group of recruited healthy elderly subjects. Patients formed two …