Support for RGS4 as a susceptibility gene for schizophrenia

NM Williams, A Preece, G Spurlock, N Norton… - Biological …, 2004 - Elsevier
BACKGROUND: The gene encoding the regulator of G-protein signaling 4 has recently
been associated with susceptibility to schizophrenia. This finding is particularly interesting,
because it was replicated within the same study and also because there are functional,
positional, and expression data to support the regulator of G-protein signaling 4 as a
schizophrenia candidate gene. Although the original report was highly suggestive, a
limitation was that the study was conducted on rather small samples. METHODS: We have …