Numerous lines of inquiry implicate connectivity as a central abnormality in schizophrenia.
Myelination and factors that affect myelination, such as the function of oligodendroglia, are
critical processes that could profoundly affect neuronal connectivity, especially given the
diffuse distribution of oligodendrocytes and the widespread distribution of brain regions that
have been implicated in schizophrenia. Multiple lines of evidence now converge to implicate
oligodendroglia and myelin in schizophrenia. Imaging and neurocytochemical evidence …