A single dominant gene still cannot account for the transmission of schizophrenia
M McGue, II Gottesman - Archives of General Psychiatry, 1989 - jamanetwork.com
To the Editor.—Holzman et al 1 have written another in a series of thought-provoking reports
describing the nature of the association between eye movement dysfunctions (EMDs) and
schizophrenia. Although these researchers have convincingly established the existence of a
familial association between EMDs and schizophrenia, we question whether their single
dominant gene model can account for the joint transmission of these two characteristics.
Holzman et al, in explicitly formulating a model for the joint transmission of schizophrenia …
describing the nature of the association between eye movement dysfunctions (EMDs) and
schizophrenia. Although these researchers have convincingly established the existence of a
familial association between EMDs and schizophrenia, we question whether their single
dominant gene model can account for the joint transmission of these two characteristics.
Holzman et al, in explicitly formulating a model for the joint transmission of schizophrenia …