Sequential tests for the detection of linkage
NE Morton - American journal of human genetics, 1955 - ncbi.nlm.nih.gov
NE Morton
American journal of human genetics, 1955•ncbi.nlm.nih.govINFORMATION ON LINKAGE in man is accumulated as a succession of samples, each of
which is typically small relative to the amount of data required to detect even moderately
close linkage. The best method of analysis for such sequential samples, in the sense of
requiring the least number of observations consistent with a given risk of error, has been
found to be a sequentialprobability ratio test (Wald, 1947). It will now be shown that this test,
in addition to minimizing the number of observations, is in other respects a useful method for …
which is typically small relative to the amount of data required to detect even moderately
close linkage. The best method of analysis for such sequential samples, in the sense of
requiring the least number of observations consistent with a given risk of error, has been
found to be a sequentialprobability ratio test (Wald, 1947). It will now be shown that this test,
in addition to minimizing the number of observations, is in other respects a useful method for …
INFORMATION ON LINKAGE in man is accumulated as a succession of samples, each of which is typically small relative to the amount of data required to detect even moderately close linkage. The best method of analysis for such sequential samples, in the sense of requiring the least number of observations consistent with a given risk of error, has been found to be a sequentialprobability ratio test (Wald, 1947). It will now be shown that this test, in addition to minimizing the number of observations, is in other respects a useful method for the detection of linkage in man.
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