Increased serum concentration of the soluble interleukin-2 receptor in cutaneous T-cell lymphoma: clinical and prognostic implications

MA Wasik, EC Vonderheid, RD Bigler… - Archives of …, 1996 - jamanetwork.com
Background and Design: The serum concentration of soluble α-chain receptor for interleukin-
2 (sIL-2R) was determined in 101 patients with cutaneous T-cell lymphoma (CTCL). Results:
The serum concentration of sIL-2R correlates positively with CTCL tumor burden as
determined by several clinical parameters (ie, clinical subtype of disease, extent of skin
involvement, T rating, and stage), by serum lactate dehydrogenase concentration, and by
Sézary cell counts in erythrodermic disease. The median value of sIL-2R in erythrodermic …