Thymus and activation-regulated chemokine (TARC/CCL17) in mycosis fungoides: serum TARC levels reflect the disease activity of mycosis fungoides

T Kakinuma, M Sugaya, K Nakamura, F Kaneko… - Journal of the American …, 2003 - Elsevier
Background: Mycosis fungoides (MF) belongs to cutaneous T-cell lymphoma and is clinically
divided into 3 stages: patch, plaque, and tumor stage. Thymus and activation-regulated
chemokine (TARC/CCL17) is a member of the CC chemokines and is a chemoattractant for
CC chemokine receptor 4 (CCR4)-and CC chemokine receptor 8 (CCR8)-expressing cells.
Objective: In this study, we examined the involvement of TARC among patients with each
stage of MF. Methods: We investigated the expression of TARC, CCR4, and CXC chemokine …