[HTML][HTML] Analysis of the presence and abundance of GABAA receptors containing two different types of α subunits in murine brain using point-mutated α subunits
D Benke, P Fakitsas, C Roggenmoser, C Michel… - Journal of Biological …, 2004 - ASBMB
γ-Aminobutyric acid, type A (GABA A) receptors are pentameric proteins of which the
majority is composed of two α subunits, two β subunits and one γ subunit. It is well
documented that two different types of α subunits can exist in a singles GABA A receptor
complex. However, information on the abundance of such GABA A receptors is rather
limited. Here we tested whether mice containing the His to Arg point mutation in the α1, α2,
or α3 subunit at positions 101, 101, and 126, respectively, which render the respective …
majority is composed of two α subunits, two β subunits and one γ subunit. It is well
documented that two different types of α subunits can exist in a singles GABA A receptor
complex. However, information on the abundance of such GABA A receptors is rather
limited. Here we tested whether mice containing the His to Arg point mutation in the α1, α2,
or α3 subunit at positions 101, 101, and 126, respectively, which render the respective …