Alterations in protein kinase A and protein kinase C levels in heart failure due to genetic cardiomyopathy.
J Wang, X Liu, AS Arneja, NS Dhalla - The Canadian journal of …, 1999 - europepmc.org
J Wang, X Liu, AS Arneja, NS Dhalla
The Canadian journal of cardiology, 1999•europepmc.orgBackground It is becoming evident that both cardiac and skeletal muscles are affected in
congestive heart failure. Although protein kinases are known to regulate cardiac function,
very little is known about their status in cardiac and skeletal muscles during the development
of congestive heart failure. Objective To determine changes in the activities and protein
levels of protein kinase A (PKA) and protein kinase C (PKC) in cardiac and skeletal muscles
in congestive heart failure due to genetic cardiomyopathy on the basis that PKA and PKC …
congestive heart failure. Although protein kinases are known to regulate cardiac function,
very little is known about their status in cardiac and skeletal muscles during the development
of congestive heart failure. Objective To determine changes in the activities and protein
levels of protein kinase A (PKA) and protein kinase C (PKC) in cardiac and skeletal muscles
in congestive heart failure due to genetic cardiomyopathy on the basis that PKA and PKC …
Background
It is becoming evident that both cardiac and skeletal muscles are affected in congestive heart failure. Although protein kinases are known to regulate cardiac function, very little is known about their status in cardiac and skeletal muscles during the development of congestive heart failure.
Objective
To determine changes in the activities and protein levels of protein kinase A (PKA) and protein kinase C (PKC) in cardiac and skeletal muscles in congestive heart failure due to genetic cardiomyopathy on the basis that PKA and PKC are crucial for protein phosphorylation.
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