Impaired insulin-stimulated nonoxidative glucose metabolism in glucose-tolerant women with previous gestational diabetes

P Damm, H Vestergaard, C Kühl, O Pedersen - American journal of …, 1996 - Elsevier
OBJECTIVE: Our purpose was to investigate insulin sensitivity and insulin secretion in
women with previous gestational diabetes. STUDY DESIGN: Twelve women with previous
gestational diabetes and 11 controls were examined by oral and intravenous glucose
tolerance tests and a hyperinsulinemic euglycemic clamp including indirect calorimetry. All
women were lean and had normal oral glucose tolerance test results. Activities of glycogen
synthase, phosphofructokinase, and hexokinase were measured in vastus lateralis muscle …