[HTML][HTML] Role of SNAP23 in insulin-induced translocation of GLUT4 in 3T3-L1 adipocytes: Mediation of complex formation between syntaxin4 and VAMP2

M Kawanishi, Y Tamori, H Okazawa, S Araki… - Journal of Biological …, 2000 - ASBMB
Both syntaxin4 and VAMP2 are implicated in insulin regulation of glucose transporter-4
(GLUT4) trafficking in adipocytes as target (t) soluble N-ethylmaleimide-sensitive factor
attachment protein receptors (SNARE) and vesicle (v)-SNARE proteins, respectively, which
mediate fusion of GLUT4-containing vesicles with the plasma membrane. Synaptosome-
associated 23-kDa protein (SNAP23) is a widely expressed isoform of SNAP25, the principal
t-SNARE of neuronal cells, and colocalizes with syntaxin4 in the plasma membrane of 3T3 …