The potential role of genes in nonalcoholic fatty liver disease

CP Day - Clinics in liver disease, 2004 - liver.theclinics.com
It is has been established that most patients with nonalcoholic fatty liver disease (NAFLD)
have one or more features of the recently characterized metabolic syndrome: central obesity,
impaired glucose tolerance, hypertension, and dyslipidemia (raised triglycerides and low
high-density lipoprotein [HDL] cholesterol)[1, 2]. In these patients, both the number of
metabolic features present and the severity of the underlying insulin resistance are
associated with more advanced disease, nonalcoholic steatohepatitis (NASH) and fibrosis …