Cell number versus cell vigor—what really matters to a regenerating skeleton?

SC Manolagas - Endocrinology, 1999 - academic.oup.com
Endocrinology, 1999academic.oup.com
“I agree with those African tribes who decorate themselves with bones. It is more to my taste
than diamonds, which are a cold and soulless shine. Whilst bone, ah bone, is the pit of a
man after the cumbering flesh has been eaten away. Bone is power. It is bone to which the
soft parts cling, from which they are, helpless, strung and held aloft to the sun, lest man be
but another slithering earth-noser... What is this tissue that has double the strength of oak?
One cubic inch of which will stand a crushing force of two tons? This substance that refuses …
“I agree with those African tribes who decorate themselves with bones. It is more to my taste than diamonds, which are a cold and soulless shine. Whilst bone, ah bone, is the pit of a man after the cumbering flesh has been eaten away. Bone is power. It is bone to which the soft parts cling, from which they are, helpless, strung and held aloft to the sun, lest man be but another slithering earth-noser... What is this tissue that has double the strength of oak? One cubic inch of which will stand a crushing force of two tons? This substance that refuses to dissolve in our body fluids, but remains intact and solid through all vicissitudes of temperature and pollution? We may be grateful for this insolubility, for it is what stands us tall.”—Richard Selzer, Mortal Lessons, Harcourt-Brace, San Diego, 1974, pp. 51–52.
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