Electron tomography: towards visualizing the molecular organization of the cytoplasm

W Baumeister - Current opinion in structural biology, 2002 - Elsevier
W Baumeister
Current opinion in structural biology, 2002Elsevier
Electron tomography of thin sections of plastic-embedded biological material provides
valuable insights into the organellar organization of cells. With the advent of automated data-
acquisition procedures, it has become possible to study radiation-sensitive specimens, such
as frozen-hydrated organelles and whole cells. This opens up exciting perspectives for
visualizing the molecular organization of the cytoplasm.
Electron tomography of thin sections of plastic-embedded biological material provides valuable insights into the organellar organization of cells. With the advent of automated data-acquisition procedures, it has become possible to study radiation-sensitive specimens, such as frozen-hydrated organelles and whole cells. This opens up exciting perspectives for visualizing the molecular organization of the cytoplasm.
Elsevier