[HTML][HTML] Structural features of the acyl chain determine self-phospholipid antigen recognition by a CD1d-restricted invariant NKT (iNKT) cell
J Rauch, J Gumperz, C Robinson, M Sköld… - Journal of Biological …, 2003 - ASBMB
Little is known about the antigen specificity of CD1d-restricted T cells, except that they
frequently recognize CD1d-expressing antigen-presenting cells in the absence of
exogenous antigen. We previously demonstrated that the 24.8. A iNKT cell hybridoma was
broadly reactive with CD1d-transfected cell lines and recognized the polar lipid fraction of a
tumor cell extract. In the present study, the antigen recognized by the 24.8. A iNKT cell
hybridoma was purified to homogeneity and identified as palmitoyl-oleoyl-sn-glycero-3 …
frequently recognize CD1d-expressing antigen-presenting cells in the absence of
exogenous antigen. We previously demonstrated that the 24.8. A iNKT cell hybridoma was
broadly reactive with CD1d-transfected cell lines and recognized the polar lipid fraction of a
tumor cell extract. In the present study, the antigen recognized by the 24.8. A iNKT cell
hybridoma was purified to homogeneity and identified as palmitoyl-oleoyl-sn-glycero-3 …