Diabetes mellitus as a hypercoagulable state: its relationship with fibrin fragments and vascular damage
LJG Frade, H De La Calle, I Alava, JL Navarro… - Thrombosis research, 1987 - Elsevier
Haemostatic variables were assessed in 43 patients, 28 insulin-dependent and 15 non
insulin-dependent. Maximum aggregation by low concentrations of adenosine diphosphate
(ADP) or arachidonic acid and elevated plasma concentrations of TxB2, Factor VIII, vWF: Ag,
RCoF and fibronectin (Fnct) indicated a hypercoagulable state. The manifestation of
vasculopathy was associated with elevated concentrations of RCoF, Fnct, Hbalc, cholesterol
and triglycerides, while impaired fibrinolysis was demonstrated by decreased t-PA levels …
insulin-dependent. Maximum aggregation by low concentrations of adenosine diphosphate
(ADP) or arachidonic acid and elevated plasma concentrations of TxB2, Factor VIII, vWF: Ag,
RCoF and fibronectin (Fnct) indicated a hypercoagulable state. The manifestation of
vasculopathy was associated with elevated concentrations of RCoF, Fnct, Hbalc, cholesterol
and triglycerides, while impaired fibrinolysis was demonstrated by decreased t-PA levels …