Receptors, antireceptor antibodies and mechanisms of insulin resistance
THE first step in the action of insulin, as in the actions of all polypeptide hormones, is binding
to receptor molecules on the plasma membrane of the cell. 1 The receptor serves to
recognize the specific hormone in the plasma, to bind it and then, as a hormone-receptor
complex, to activate the cell. In this seminar, we briefly discuss the nature of peptide
hormone receptors and their role in hormone action and then describe some recently
identified clinical disorders, which have been clarified through studies of hormone-receptor …
to receptor molecules on the plasma membrane of the cell. 1 The receptor serves to
recognize the specific hormone in the plasma, to bind it and then, as a hormone-receptor
complex, to activate the cell. In this seminar, we briefly discuss the nature of peptide
hormone receptors and their role in hormone action and then describe some recently
identified clinical disorders, which have been clarified through studies of hormone-receptor …
THE first step in the action of insulin, as in the actions of all polypeptide hormones, is binding to receptor molecules on the plasma membrane of the cell.1 The receptor serves to recognize the specific hormone in the plasma, to bind it and then, as a hormone-receptor complex, to activate the cell. In this seminar, we briefly discuss the nature of peptide hormone receptors and their role in hormone action and then describe some recently identified clinical disorders, which have been clarified through studies of hormone-receptor interaction.
Consistent with their role as mediators of the biologic effects of hormones is . . .
The New England Journal Of Medicine