[HTML][HTML] Gβγ binds directly to the G protein-gated K+ channel, IKACh

G Krapivinsky, L Krapivinsky, K Wickman… - Journal of Biological …, 1995 - ASBMB
The cardiac G protein-gated K+ channel, I KACh, is activated by application of purified and
recombinant β and γ subunits (Gβγ) of heterotrimeric G proteins to excised inside-out
patches from atrial membranes (Logothetis, DE, Kurachi, Y., Galper, J., Neer, E., and
Clapham, DE (1987) Nature 325, 321-326; Wickman, K.,[Medline] Iniguez-Lluhi, J.,
Davenport, P., Taussig, RA, Krapivinsky, GB, Linder, ME, Gilman, A., and Clapham, DE
(1994) Nature 368, 255-257). Cardiac I [Medline] KACh is composed of two inward rectifier …