[HTML][HTML] Model for the regulation of energy balance and adiposity by the central nervous system

MW Schwartz, DG Baskin, KJ Kaiyala… - The American journal of …, 1999 - Elsevier
In 1995, we described a new model for adiposity regulation. Since then, data regarding the
biology of body weight regulation has accumulated at a remarkable rate and has both
modified and strengthened our understanding of this homeostatic system. In this review we
integrate new information into a revised model for further understanding this important
regulatory process. Our model of energy homeostasis proposes that long-term adiposity-
related signals such as insulin and leptin influence the neuronal activity of central effector …