[HTML][HTML] Identification of overlapping AP-2/NF-κB-responsive elements on the rat cholecystokinin gene promoter
PL Katsel, RJ Greenstein - Journal of Biological Chemistry, 2001 - ASBMB
In this study we evaluate both proximal and more distal transcriptional regulation of the 5′
flanking region of the rat cholecystokinin gene in transfected GH3 (rat pituitary tumor) cells.
Transcriptional activity was measured on the intact (− 400 to+ 73) 5′ flanking region of
cholecystokinin (CCK), as well as with DNA constructs, which were deleted in both the
conventional 5′ to 3′, as well as an unconventional 3′ to 5′ direction. Our in
vivostudies indicate complex phorbol ester and forskolin interactions in the 10-base pair …
flanking region of the rat cholecystokinin gene in transfected GH3 (rat pituitary tumor) cells.
Transcriptional activity was measured on the intact (− 400 to+ 73) 5′ flanking region of
cholecystokinin (CCK), as well as with DNA constructs, which were deleted in both the
conventional 5′ to 3′, as well as an unconventional 3′ to 5′ direction. Our in
vivostudies indicate complex phorbol ester and forskolin interactions in the 10-base pair …