Hepatocyte nuclear factor 3/fork head or" winged helix" proteins: a family of transcription factors of diverse biologic function.
E Lai, KL Clark, SK Burley… - Proceedings of the …, 1993 - National Acad Sciences
E Lai, KL Clark, SK Burley, JE Darnell Jr
Proceedings of the National Academy of Sciences, 1993•National Acad SciencesA family of transcription factors, first identified as hepatocyte nuclear factors (HNF-3 alpha,-3
beta, and-3 gamma) and as a homeotic Drosophila mutant, fork head, has been intensively
studied for the past 4 years. Important findings have emerged about the structure of the DNA-
binding portion of the proteins as well as biologic discoveries about the diversity of the family
and its implied role in early development.
beta, and-3 gamma) and as a homeotic Drosophila mutant, fork head, has been intensively
studied for the past 4 years. Important findings have emerged about the structure of the DNA-
binding portion of the proteins as well as biologic discoveries about the diversity of the family
and its implied role in early development.
A family of transcription factors, first identified as hepatocyte nuclear factors (HNF-3 alpha, -3 beta, and -3 gamma) and as a homeotic Drosophila mutant, fork head, has been intensively studied for the past 4 years. Important findings have emerged about the structure of the DNA-binding portion of the proteins as well as biologic discoveries about the diversity of the family and its implied role in early development.
National Acad Sciences