5'-terminal structure of poliovirus polyribosomal RNA is pUp.
MJ Hewlett, JK Rose… - Proceedings of the …, 1976 - National Acad Sciences
MJ Hewlett, JK Rose, D Baltimore
Proceedings of the National Academy of Sciences, 1976•National Acad SciencesPoliovirus RNA purified from virus-specific polyribosomes does not contain m7G in a 5'-5'-
pyrophosphate linkage at its 5'-end. The only potential 5'-end found in ribonuclease digests
of this RNA is pUp, which is present in a yield of 1 mole/mole of poliovirus RNA. We
conclude that a 5'-terminal m7G is not required for translation of at least one RNA species in
animal cells.
pyrophosphate linkage at its 5'-end. The only potential 5'-end found in ribonuclease digests
of this RNA is pUp, which is present in a yield of 1 mole/mole of poliovirus RNA. We
conclude that a 5'-terminal m7G is not required for translation of at least one RNA species in
animal cells.
Poliovirus RNA purified from virus-specific polyribosomes does not contain m7G in a 5'-5'-pyrophosphate linkage at its 5'-end. The only potential 5'-end found in ribonuclease digests of this RNA is pUp, which is present in a yield of 1 mole/mole of poliovirus RNA. We conclude that a 5'-terminal m7G is not required for translation of at least one RNA species in animal cells.
National Acad Sciences