Psoriasis of early and late onset: characterization of two types of psoriasis vulgaris
T Henseler, E Christophers - Journal of the American Academy of …, 1985 - Elsevier
In 2,147 patients suffering from psoriasis, evaluation of the age of onset revealed two peaks,
one occurring at the age of 16 years (female) or 22 years (males) and a second peak at the
age of 60 years (female) or 57 years (males). Human lymphocyte antigen (HLA) tissue
typing in 112 randomly assigned patients showed that HLA-Cw6, known to be at
disequilibrium in psoriasis, is present in 85.3% of patients with early onset. In contrast,
14.7% patients with late onset showed this marker. Parents (father or mother) were affected …
one occurring at the age of 16 years (female) or 22 years (males) and a second peak at the
age of 60 years (female) or 57 years (males). Human lymphocyte antigen (HLA) tissue
typing in 112 randomly assigned patients showed that HLA-Cw6, known to be at
disequilibrium in psoriasis, is present in 85.3% of patients with early onset. In contrast,
14.7% patients with late onset showed this marker. Parents (father or mother) were affected …