Biology of regional body fat distribution: relationship to non-insulin-dependent diabetes mellitus.
AH Kissebah, AN Peiris - Diabetes/metabolism reviews, 1989 - europepmc.org
AH Kissebah, AN Peiris
Diabetes/metabolism reviews, 1989•europepmc.orgOur studies support the view that body fat distribution and the accompanying metabolic
abnormalities could be exacerabated by variability in the androgenic/estrogenic balance.
Sensitivity to the androgenic milieu might be initiated by an early developmental aberration
in sexual dimorphism. The possible direct and indirect sites of interaction between
androgenic activity and the abnormal metabolic pathways in upper body obesity are
summarized in Figure 19.
abnormalities could be exacerabated by variability in the androgenic/estrogenic balance.
Sensitivity to the androgenic milieu might be initiated by an early developmental aberration
in sexual dimorphism. The possible direct and indirect sites of interaction between
androgenic activity and the abnormal metabolic pathways in upper body obesity are
summarized in Figure 19.
Our studies support the view that body fat distribution and the accompanying metabolic abnormalities could be exacerabated by variability in the androgenic/estrogenic balance. Sensitivity to the androgenic milieu might be initiated by an early developmental aberration in sexual dimorphism. The possible direct and indirect sites of interaction between androgenic activity and the abnormal metabolic pathways in upper body obesity are summarized in Figure 19.
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