Oncogenic proteins as tumor antigens

ML Disis, MA Cheever - Current opinion in immunology, 1996 - Elsevier
ML Disis, MA Cheever
Current opinion in immunology, 1996Elsevier
Human immune responses to oncogenic proteins have been reported and are continuing to
be defined. Immunity to nonmutated overexpressed oncoproteins as well as to mutated or
unique cancer-specific oncoproteins has been identified. Immune system based treatments
targeting oncogenic proteins have shown therapeutic efficacy in animals models and are
currently being translated into human clinical trials
Human immune responses to oncogenic proteins have been reported and are continuing to be defined. Immunity to nonmutated overexpressed oncoproteins as well as to mutated or unique cancer-specific oncoproteins has been identified. Immune system based treatments targeting oncogenic proteins have shown therapeutic efficacy in animals models and are currently being translated into human clinical trials
Elsevier