[HTML][HTML] Dysbindin, a novel coiled-coil-containing protein that interacts with the dystrobrevins in muscle and brain
MA Benson, SE Newey, E Martin-Rendon… - Journal of Biological …, 2001 - ASBMB
The dystrophin-associated protein complex (DPC) is required for the maintenance of muscle
integrity during the mechanical stresses of contraction and relaxation. In addition to
providing a membrane scaffold, members of the DPC such as the α-dystrobrevin protein
family are thought to play an important role in intracellular signal transduction. To gain
additional insights into the function of the DPC, we performed a yeast two-hybrid screen for
dystrobrevin-interacting proteins. Here we describe the identification of a dysbindin, a novel …
integrity during the mechanical stresses of contraction and relaxation. In addition to
providing a membrane scaffold, members of the DPC such as the α-dystrobrevin protein
family are thought to play an important role in intracellular signal transduction. To gain
additional insights into the function of the DPC, we performed a yeast two-hybrid screen for
dystrobrevin-interacting proteins. Here we describe the identification of a dysbindin, a novel …