[CITATION][C] Cleaning up on β-catenin
Y Nakamura - Nature Medicine, 1997 - nature.com
Nature Medicine, 1997•nature.com
Untitled Page 1 Page 2 © 1997 Nature Publishing Group http://www.nature.com/naturemedicine
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.. mologue of the Drosophila Discs Large tumor suppressor protein). But which of these
proteins plays a significant role in abnormal cell growth when APC is mutated? Among the
candidate proteins, the physiological role of 13-catenin has been most intensively
examined because of its interaction with cadherin adhesion molecules, and also because it …
NEWS & VIEWS .................................................................................................................................................................................................
.. mologue of the Drosophila Discs Large tumor suppressor protein). But which of these
proteins plays a significant role in abnormal cell growth when APC is mutated? Among the
candidate proteins, the physiological role of 13-catenin has been most intensively
examined because of its interaction with cadherin adhesion molecules, and also because it …
Inactivation of the APC tumor suppressor gene in melanoma and colon cancer results in increased transcriptional activity mediated by β-catenin.
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