Purpose: In the current series of experiments we have characterized cell proliferation
leading to vascular lesion formation in a porcine model for post-angioplasty restenosis adn
examined the mechanism of action intravascular beta irradiation in the prevention of lesion
formation in this model. Methods and Materials: Juvenile male pigs were subjected to
balloon overstretch injury of the left anterior descending and circumflex coronary arteries
using clinical angioplasty catheters. Proliferating cells were labelled by injections of 50 …