Opposite effects on cholesterol metabolism and their mechanisms induced by dietary oleic acid and palmitic acid in hamsters
K Hitoshi, H Kozo, T Shingu, K Yoshio, H Ohtani… - … et Biophysica Acta (BBA …, 1995 - Elsevier
The effects of dietary oleic acid on cholesterol metabolism were investigated and compared
with those of palmitic acid in hamsters. Addition of 5% oleic acid to a 0. l% cholesterol-
supplemented diet decreased plasma total cholesterol, very low density lipoprotein (VLDL)
cholesterol, and low density lipoprotein (LDL) cholesterol, increased hepatic LDL receptor
activity, and decreased plasma cholesteryl ester transfer protein (CETP) activity in
comparison with 0.1% cholesterol alone. In contrast, addition of 5% palmitic acid to a 0.1 …
with those of palmitic acid in hamsters. Addition of 5% oleic acid to a 0. l% cholesterol-
supplemented diet decreased plasma total cholesterol, very low density lipoprotein (VLDL)
cholesterol, and low density lipoprotein (LDL) cholesterol, increased hepatic LDL receptor
activity, and decreased plasma cholesteryl ester transfer protein (CETP) activity in
comparison with 0.1% cholesterol alone. In contrast, addition of 5% palmitic acid to a 0.1 …