Long-term management of atopic dermatitis in infants with topical pimecrolimus, a nonsteroid anti-inflammatory drug

A Kapp, K Papp, A Bingham, R Fölster-Holst… - Journal of Allergy and …, 2002 - Elsevier
Background: Pimecrolimus cream 1%(Elidel, SDZ ASM 981), a nonsteroid selective inhibitor
of inflammatory cytokines, is effective in the treatment of atopic dermatitis (AD). In this study
we compared early intervention with pimecrolimus cream with treatment with a vehicle
control. Objective: The purpose of this investigation was to assess whether early treatment in
infants of AD signs/symptoms with pimecrolimus could influence long-term outcome by
preventing disease flares. Methods: In this 1-year, double-blind controlled study, 251 infants …