[HTML][HTML] Transactivation of vascular endothelial growth factor (VEGF) receptor Flk-1/KDR is involved in sphingosine 1-phosphate-stimulated phosphorylation of Akt …
T Tanimoto, ZG Jin, BC Berk - Journal of Biological Chemistry, 2002 - ASBMB
Sphingosine 1-phosphate (S1P) and vascular endothelial growth factor (VEGF) elicit
numerous biological responses including cell survival, growth, migration, and differentiation
in endothelial cells mediated by the endothelial differentiation gene, a family of G-protein-
coupled receptors, and fetal liver kinase-1/kinase-insert domain-containing receptor (Flk-
1/KDR), one of VEGF receptors, respectively. Recently, it was reported that S1P or VEGF
treatment of endothelial cells leads to phosphorylation at Ser-1179 in bovine endothelial …
numerous biological responses including cell survival, growth, migration, and differentiation
in endothelial cells mediated by the endothelial differentiation gene, a family of G-protein-
coupled receptors, and fetal liver kinase-1/kinase-insert domain-containing receptor (Flk-
1/KDR), one of VEGF receptors, respectively. Recently, it was reported that S1P or VEGF
treatment of endothelial cells leads to phosphorylation at Ser-1179 in bovine endothelial …