Interleukin (IL)-6, IL-8 and IL-10 in serum and CSF of Trypanosoma brucei gambiense sleeping sickness patients before and after treatment

V Lejon, J Lardon, G Kenis, L Pinoges, D Legros… - Transactions of the …, 2002 - Elsevier
Serum and cerebrospinal fluid (CSF) concentrations of interleukin (IL)-6, IL-8, IL-10, tumour
necrosis factor-α and interferon-γ were determined in 46 Trypanosoma brucei gambiense
sleeping sickness patients in DR Congo, before and after treatment. According to their CSF
cell number before treatment, patients were classified as early-stage (0–5 cells/μL),
intermediate-stage (6–20 cells/μL) or late-stage patients (> 20 cells/μL). In serum, slightly
higher IL-8 concentrations were found in early-stage patients compared to intermediateor …