[HTML][HTML] Radiation pneumonitis in mice: a severe injury model for pneumocyte engraftment from bone marrow
ND Theise, O Henegariu, J Grove, J Jagirdar… - Experimental …, 2002 - Elsevier
OBJECTIVE: To better understand the process by which pneumocytes can be derived from
bone marrow cells, we investigated the in vivo kinetics of such engraftment following lethal
irradiation. METHODS: A cohort of lethally irradiated B6D2F1 female mice received whole
bone marrow transplants (BMT) from age-matched male donors and were sacrificed at days
1, 3, 5, and 7 and months 2, 4, and 6 post-BMT (n= 3 for each time point). Additionally, 2
female mice who had received 200 male fluorescence-activated cell sorter (FACS)-sorted …
bone marrow cells, we investigated the in vivo kinetics of such engraftment following lethal
irradiation. METHODS: A cohort of lethally irradiated B6D2F1 female mice received whole
bone marrow transplants (BMT) from age-matched male donors and were sacrificed at days
1, 3, 5, and 7 and months 2, 4, and 6 post-BMT (n= 3 for each time point). Additionally, 2
female mice who had received 200 male fluorescence-activated cell sorter (FACS)-sorted …