Insulin/IGF signalling and ageing: seeing the bigger picture
D Gems, L Partridge - Current opinion in genetics & development, 2001 - Elsevier
D Gems, L Partridge
Current opinion in genetics & development, 2001•ElsevierAlthough the underlying mechanisms of ageing are not understood, it is known that the
longevity of the nematode Caenorhabditis elegans is modulated by an insulin/IGF-signalling
pathway. The focus now is on how this pathway is regulated, how it controls nematode
ageing, and how this relates to the ageing process in higher animals.
longevity of the nematode Caenorhabditis elegans is modulated by an insulin/IGF-signalling
pathway. The focus now is on how this pathway is regulated, how it controls nematode
ageing, and how this relates to the ageing process in higher animals.
Although the underlying mechanisms of ageing are not understood, it is known that the longevity of the nematode Caenorhabditis elegans is modulated by an insulin/IGF-signalling pathway. The focus now is on how this pathway is regulated, how it controls nematode ageing, and how this relates to the ageing process in higher animals.
Elsevier