Novel ligands for P2 receptor subtypes in innervated tissues
G Lambrecht, S Damer, B Niebel, S Czeche… - Progress in Brain …, 1999 - Elsevier
Publisher Summary The studies with novel P2 receptor agonists and antagonists point out
that the P2Y receptor in the taenia coli is different from the P2Y, receptor in turkey
erythrocytes. Among suramin analogs, the properties of P2 receptor subtype blockade and
ecto-nucleotidase inhibition appear to be controlled by different structural parameters: the
molecular size of the compounds, the position of the sulfonic acid residues in the
naphthalene rings, the substitution pattern of the benzoyl moieties, and the 3′-or 4 …
that the P2Y receptor in the taenia coli is different from the P2Y, receptor in turkey
erythrocytes. Among suramin analogs, the properties of P2 receptor subtype blockade and
ecto-nucleotidase inhibition appear to be controlled by different structural parameters: the
molecular size of the compounds, the position of the sulfonic acid residues in the
naphthalene rings, the substitution pattern of the benzoyl moieties, and the 3′-or 4 …