Fungal infection in chronic granulomatous disease: the importance of the phagocyte in defense against fungi
MS Cohen, RE Isturiz, HL Malech, RK Root… - The American journal of …, 1981 - Elsevier
Among 245 cases of chronic granulomatous disease which were evaluated, fungal infection
occurred in 20.4 percent. Fungi encountered include Aspergillus, Torulopsis and Candida.
In 18 percent of the patients with fungal infection, the disease was limited to soft tissue or
bone; all did well. Most of the patients had fungal pneumonia and/or widely disseminated
disease; diagnosis was usually confirmed by open lung biopsy. Patients with pneumonia or
disseminated disease who received no therapy succumbed to infection, whereas more than …
occurred in 20.4 percent. Fungi encountered include Aspergillus, Torulopsis and Candida.
In 18 percent of the patients with fungal infection, the disease was limited to soft tissue or
bone; all did well. Most of the patients had fungal pneumonia and/or widely disseminated
disease; diagnosis was usually confirmed by open lung biopsy. Patients with pneumonia or
disseminated disease who received no therapy succumbed to infection, whereas more than …