[CITATION][C] Ras regulation. NF is enough of GAP.
G Bollag, F McCormick - Nature, 1992 - europepmc.org
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NF is enough of GAP.
G Bollag, F McCormick - Nature, 1992 - search.ebscohost.com
Abstract Discusses neurofibromatosis type 1 (NF1), a genetic disease characterized by
benign and sometimes malignant tumors that originate in the neural crest. Identification of
the gene which is defective in NF1 patients; Neurofibromin as a GTPase-activating protein
(GAP) for the p21 ras proto-oncogene product that converts active GTP-bound p21 ras to its
inactive GDP-bound state; Study by Basu, et al; More.
benign and sometimes malignant tumors that originate in the neural crest. Identification of
the gene which is defective in NF1 patients; Neurofibromin as a GTPase-activating protein
(GAP) for the p21 ras proto-oncogene product that converts active GTP-bound p21 ras to its
inactive GDP-bound state; Study by Basu, et al; More.