Adhesion assembly, disassembly and turnover in migrating cells–over and over and over again
DJ Webb, JT Parsons, AF Horwitz - Nature cell biology, 2002 - nature.com
DJ Webb, JT Parsons, AF Horwitz
Nature cell biology, 2002•nature.comCell migration is an integrated process that requires the continuous, coordinated formation
and disassembly of adhesions. These processes are complex and require a regulated
interaction of numerous molecules, and the activation of specific signalling pathways. Even
though understanding these processes is challenging, important insights are beginning to
emerge, and the technology to facilitate significant advances in this area is now in place.
and disassembly of adhesions. These processes are complex and require a regulated
interaction of numerous molecules, and the activation of specific signalling pathways. Even
though understanding these processes is challenging, important insights are beginning to
emerge, and the technology to facilitate significant advances in this area is now in place.
Abstract
Cell migration is an integrated process that requires the continuous, coordinated formation and disassembly of adhesions. These processes are complex and require a regulated interaction of numerous molecules, and the activation of specific signalling pathways. Even though understanding these processes is challenging, important insights are beginning to emerge, and the technology to facilitate significant advances in this area is now in place.
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