Adipose-cell size and immunoreactive insulin levels in obese and normal-weight adults
JS Stern, N Hollander, BR Batchelor, CK Cohn… - The Lancet, 1972 - Elsevier
JS Stern, N Hollander, BR Batchelor, CK Cohn, J Hirsch
The Lancet, 1972•ElsevierThe relationship between adipose-cell size and plasma levels of immunoreactive insulin
(IRI) was studied in 73 normal and obese individuals and in 12 obese patients before and
after weight reduction. A strong positive correlation was found between adipose-cell size
and fasting IRI in both groups. This relation exists despite the widely differing degrees of
obesity (and, therefore, their probable different total carbohydrate intakes). It is suggested
that the increased adipose-cell size seen in obesity could sensitise the pancreas to produce …
(IRI) was studied in 73 normal and obese individuals and in 12 obese patients before and
after weight reduction. A strong positive correlation was found between adipose-cell size
and fasting IRI in both groups. This relation exists despite the widely differing degrees of
obesity (and, therefore, their probable different total carbohydrate intakes). It is suggested
that the increased adipose-cell size seen in obesity could sensitise the pancreas to produce …
Abstract
The relationship between adipose-cell size and plasma levels of immunoreactive insulin (I.R.I.) was studied in 73 normal and obese individuals and in 12 obese patients before and after weight reduction. A strong positive correlation was found between adipose-cell size and fasting I.R.I. in both groups. This relation exists despite the widely differing degrees of obesity (and, therefore, their probable different total carbohydrate intakes). It is suggested that the increased adipose-cell size seen in obesity could sensitise the pancreas to produce more insulin.
Elsevier