[HTML][HTML] Tissue plasminogen activator for acute ischemic stroke

… of Neurological Disorders and Stroke rt … - … England Journal of …, 1995 - Mass Medical Soc
Background Thrombolytic therapy for acute ischemic stroke has been approached
cautiously because there were high rates of intracerebral hemorrhage in early clinical trials.
We performed a randomized, double-blind trial of intravenous recombinant tissue
plasminogen activator (t-PA) for ischemic stroke after recent pilot studies suggested that t-PA
was beneficial when treatment was begun within three hours of the onset of stroke. Methods
The trial had two parts. Part 1 (in which 291 patients were enrolled) tested whether t-PA had …

[CITATION][C] Tissue plasminogen activator for acute ischemic stroke

NINDS rt-PA Stroke Study Group - N Engl J Med, 1995 - cir.nii.ac.jp
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