A scanning and transmission electron microscopic study of the surfaces of intrauterine contraceptive devices

TJ Marrie, JW Costerton - American journal of obstetrics and gynecology, 1983 - Elsevier
We studied 10 intrauterine contraceptive devices by scanning and transmission electron
microscopy. All the devices had material adherent to them. The amount of this material
varied considerably. Many different morphologic types of bacteria were observed adherent
to the devices, often buried in a thick biofilm. Occasionally a microcolony containing only a
single bacterial morphotype was observed. Electron microprobe analysis revealed the
presence of calcium in the biofilm formed by bacterial colonization. Very few types of …