Mechanisms linking angiotensin II and atherogenesis

WB Strawn, CM Ferrario - Current opinion in lipidology, 2002 - journals.lww.com
WB Strawn, CM Ferrario
Current opinion in lipidology, 2002journals.lww.com
Inhibition of the actions of angiotensin II serves a dual purpose: indirectly through reduction
of mechanical stress on the vascular wall, and directly by diminished stimulation for vascular
restructuring and remodeling. Collectively, data from studies published over the last year
confirm and extend the notion that angiotensin II is a true cytokine prevalent at all stages of
atherogenesis.
Summary
Inhibition of the actions of angiotensin II serves a dual purpose: indirectly through reduction of mechanical stress on the vascular wall, and directly by diminished stimulation for vascular restructuring and remodeling. Collectively, data from studies published over the last year confirm and extend the notion that angiotensin II is a true cytokine prevalent at all stages of atherogenesis.
Lippincott Williams & Wilkins