[HTML][HTML] Progression of Hepatic Stellate Cell Activation Is Associated with the Level of Oxidative Stress Rather Than Cytokines during CCI4-induced Fibrogenesis
KY Kim, I Choi, SS Kim - Molecules and cells, 2000 - Elsevier
In order to identify a fibrogenic factor associated with the potential of hepatic stellate cells
(HSC) activation that arises during the CC1 4-induced fibrogenic process, the relationship
between the activation of HSC and levels of several fibrogenic factors were investigated.
After isolation of HSC from the liver at different stages of CC1 4 intoxication, the activation of
HSC was assessed by the expression of a-smooth muscle actin. Levels of cytokines and
oxidative stress in liver homogenates and plasma were measured by enzyme linked …
(HSC) activation that arises during the CC1 4-induced fibrogenic process, the relationship
between the activation of HSC and levels of several fibrogenic factors were investigated.
After isolation of HSC from the liver at different stages of CC1 4 intoxication, the activation of
HSC was assessed by the expression of a-smooth muscle actin. Levels of cytokines and
oxidative stress in liver homogenates and plasma were measured by enzyme linked …