Molecular manipulation of neural precursors in situ: induction of adult cortical neurogenesis

P Arlotta, SS Magavi, JD Macklis - Experimental gerontology, 2003 - Elsevier
Over the past three decades, research exploring potential neuronal replacement therapies
have focused on replacing lost neurons by transplanting cells or grafting tissue into
diseased regions of the brain. Over most of the past century of modern neuroscience, it was
thought that the adult brain was completely incapable of generating new neurons. However,
in the last decade, the development of new techniques has resulted in an explosion of new
research showing that neurogenesis, the birth of new neurons, normally occurs in two …