Findings over the past decade demonstrating persistent neurogenesis in the adult brain
have overturned dogma, provoked reevaluation of cellular plasticity in the mature brain and
raised hopes for novel approaches to brain repair. Recent discoveries reveal that
neurogenesis is regulated by environmental stimuli and can be responsive to brain injury.
This cellular plasticity may indicate a possible endogenous repair program. By
understanding the mechanisms involved, it may be possible to harness this plasticity to …